Lefno (20 mg) Tablet Side Effects and usage

Lefno (20 mg) - Leflunomide- Tablet is manufactured by IPCA Laboratories Ltd. and the main constituent generic drug is Leflunomide- 20 mg.

Lefno (20 mg) Tablet Medicine Details

Side Effects

Headache, dizziness, weakness, bronchitis, alopecia, rash, dry skin, eczema, pruritus, hypokalemia, weight loss, arthralgia, back pain, joint disorder, leg cramps, pneumonia, respiratory infection, rhinitis, sinusitis, chest pain, hypertension, diarrhoea, nausea, abdominal pain, synovitis, tenosynovitis, paresthesia, allergic reactions, flu like syndrome abnormal liver enzymes/hepatotoxicity, anorexia, dyspepsia, gastroenteritis, mouth ulcers, vomiting and infections.


in active moderate to severe rheumatoid arthritis and psoriatic arthritis.

Contra Indications

Hypersensitivity, severe immunodificency states e.
AIDS, impaired bone marrow function or significant anaemia, leukopenia or thrombocytiopenia due to causes other than rheumatoid arthritis, severe uncontrolled infections, impairment of liver function, pregnancy and lactation, severe hypoproteinemia.
Stevens-Johnson syndrome, toxic epidermal necrolysis.


Liver function monitoring.
Not recommended for patients with severe immunodeficiency, bone marrow dysplasia or severe uncontrolled infections.
Not recommended in below the age of 18 years and elderly.
Renal and hepatic impairment and lactation.
Monitor blood counts and BP regularly.
Avoid alcohol.


The cost of the drug per 1 Tablet is Rs.17.8 in India as of date.


Lefno (20 mg) Tablet mainly contains the generic formulation called as Leflunomide- 20 mg.

Medicine Name: Lefno (20 mg) Tablet
Manufacturer: IPCA Laboratories Ltd.
Generic Molecule: Leflunomide

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